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Journal of the National Cancer Institute Advance Access originally published online on June 24, 2008
JNCI Journal of the National Cancer Institute 2008 100(13):914-917; doi:10.1093/jnci/djn229
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© Oxford University Press 2008.

NEWS

Mapping Pathways From Stress to Cancer Progression

Karen Ross

The first 150 words of the full text of this article appear below.

Using in vitro, animal, and human clinical approaches, researchers are beginning to understand the relationship between psychological stress and cancer progression at the biochemical and molecular levels.

The focus of many of these studies is basic biology—the experience of stress and changes in gene expression that may be associated with tumor progression. "We’re very much interested in taking an incremental approach and elucidating potential biological processes that might be involved," said Paige McDonald, Ph.D., chief of the National Cancer Institute’s Basic and Biobehavioral Research Branch, which funds research on stress and cancer. "Our goal is to support very sophisticated mechanistic studies, with the eventual goal of using those basic science data to develop effective interventions."

Earlier studies on stress and cancer often looked for associations between chronic psychological stress, such as depression, anxiety, or loneliness, and the incidence or course of cancer in humans. The results of these studies have . . . [Full Text of this Article]

Stress, Glucocorticoids, and Breast Cancer

Catecholamines

Intervention


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